Which intervention is most effective if inflow failure during peritoneal dialysis is caused by constipation?

The most effective intervention when inflow failure during peritoneal dialysis is caused by constipation is to induce peristalsis with a laxative. Constipation can lead to increased abdominal pressure, which may obstruct the peritoneal dialysis catheter and prevent proper inflow of the dialysis solution into the peritoneal cavity. By administering a laxative, peristalsis is stimulated, promoting bowel movements that can alleviate the pressure in the abdomen and clear any obstruction related to constipation. This approach directly addresses the underlying issue causing the inflow failure.

Increasing the dialysate volume may not be beneficial in this scenario, as it does not directly resolve the obstruction caused by constipation. Changing the catheter is a more invasive procedure that may not be necessary if the issue can be resolved by treating the constipation. Manual drainage can help in specific cases of fluid obstruction, but it does not tackle the root cause if the inflow failure is due to constipation. Thus, using a laxative to induce peristalsis is the most effective strategy in this situation.